Blue Key

Blue dye, blue skin.

Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways.

Methylene blue (MB) has been used clinically for about a century to treat numerous ailments. We show that MB and other diaminophenothiazines extend the life span of human IMR90 fibroblasts in tissue culture by >20 population doubling (PDLs). MB delays senescence at nM levels in IMR90 by enhancing mitochondrial function. MB increases mitochondrial complex IV by 30%, enhances cellular oxygen cons...

Red Blue Green Yellow Green Red Blue Red Yellow Green Red Blue Green Blue Red Green

Consider two adolescents: Person One and Person Two. Person One has never used substances and exhibits relatively few behavioral (conduct) problems. On the other hand, Person Two uses substances frequently and more commonly exhibits poor conduct. If you were to guess, which of the individuals would you expect to have lower overall judgment and self-regulation? If you answered Person Two, your i...

Blue Swarm Sentinel and Blue Swarm 2

This paper describes the Utah State University (USU) entry in the 2002 robotic Urban Search and Rescue (USAR) competition, hosted by the American Association for Artificial Intelligence (AAAI). More importantly, it also describes the problems the team encountered in preparing for this year’s competition, the lessons learned, and plans for the 2003 USAR competition. Description of the 2002 Entry...

Editorial: Blue on blue doesn't work.

However brilliant a scientist is, however incisive their mind and however elegant their experiments, they must be able to communicate effectively. The ability to write fluently, to inspire an audience in a lecture hall, and to listen carefully and argue cogently face-to-face with a sceptic are all important. Maybe some people believe that it’s only important to impress the journal referees and ...